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Oral dispersible, "Drug "Delivery systems, the oral thin film"

 

Based on the transdermal patch technologies, the oral thin film is a modern method for oral drug delivery. The distribution mechanism consists of a very thin oral strip mounted on the patient's tongue or some other oral mucosal tissue. As the film is wet with saliva, it quickly hydrates and adheres to the application spot. It quickly degrades and dissolves to release the medication for oromucosal absorption.

 

Oral Thin Films (OTF)

 

Oral films also referred to as oral wafers in the literature, are a form of flat film placed in the mouth. Dissolvable oral thin films (OTFs) or oral strips (OS) emerged from the confection and oral care industries in the form of breath strips over the last few years and have become a new and generally recognized form of supplying vitamins and personal care products. OTFs are now a well-established and widely used technology for the systemic delivery of APIs in over-the-counter (OTC) products, and they are in the early stages of growth for prescription drugs. This is partially due to the popularity of commercial air freshener products in the United States, such as Listerine Pocket Packs. To generate a 50-200 mm film, these devices use a variety of hydrophilic polymers. According to reports, this film can contain soluble, insoluble, or taste-masked drug compounds. The film is made as a large sheet, then sliced into individual dosage units and packaged in several pharmaceutically appropriate formats.